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KMID : 0360220200610030307
Journal of the Korean Ophthalmological Society
2020 Volume.61 No. 3 p.307 ~ p.312
Regression of Neovascularization after Using Only Intraocular Pressure-lowering Medications in Neovascular Glaucoma
Lee Sang-Wook

Kim Ko-Eun
Abstract
Purpose: To report a case of neovascular glaucoma after intraocular lens iris fixation, in which the neovascularization of the iris and the anterior chamber improved with only intraocular pressure (IOP) lowering agents, without treatment of the underlying cause.

Case summary: A 74-year-old woman who had undergone bilateral cataract surgery presented with left ocular pain and headache that started 3 days previously. At the initial examination, the best-corrected visual acuity was 0.9, and the IOP was 38 mmHg in the left eye. Slit-lamp examination of the left eye revealed diffuse iris neovascularization and several polypropylene suture knots fixated in the superior and inferior iris. Gonioscopic examination revealed angle neovascularization in all quadrants, with focal peripheral anterior synechia in the inferior quadrant. Fundus examination presented inferior neuroretinal rim thinning and an inferior retinal nerve fiber layer defect in the left eye. Fluorescent angiography showed no ischemic retinal lesions, with the exception of several retinal microaneurysms. Six months after topical IOP-lowering treatment in the left eye, the IOP was 10 mmHg, and neovascularization of the iris and angle had regressed completely.

Conclusions: In the case of early-stage neovascular glaucoma with partial angle closure not associated with retinal ischemia, IOP-lowering treatment can be effective without other invasive procedures.
KEYWORD
Angle neovascularization, Intraocular lens fixation, Intraocular pressure-lowering medication, Iris neovascularization, Neovascular glaucoma
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